Viridian High Two B-Complex

Viridian High Two B-Complex

  • £8.15


Vitamin B2

(Riboflavin)

Riboflavin functions in two important enzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These enzymes act as cofactors for a wide variety of oxidative enzyme systems, and are central to energy production, drug metabolism, and lipid metabolism.

  •  MIGRAINE it has been suggested that the cause of migraine is a reduction of energy productionwithinthemitochondriaofcerebralbloodvessels. Astudyinvolving49patients sufferingfrommigraineused400mgofriboflavindailyforatleastthreemonths. Afterthethree months there was an overall improvement in 68% of the patients using riboflavin.

  •  ANTIOXIDANT – riboflavin has powerful antioxidant potential due its ability to regenerate GLUTATHIONE via glutathione reductase. Riboflavin deficiency is associated with increased lipid peroxidation; supplementation of riboflavin can inhibit this process.

  •  NEUROTRANSMITTER PRODUCTION – important neurotransmitters such as DOPAMINE are riboflavin dependent.

  •  ENERGY PRODUCTION (ATP) FAD plays a crucial role in energy production within the Kreb’s cycle, where it helps generate an enzyme converting succinate into fumarate.

    Dosage - No toxicity or side effects of riboflavin have been demonstrated.

    Potential applications - Riboflavin deficiency – characterised by; weakness, fatigue, mouth pain and tenderness, eye burning and itching, personality changes, cheilosis, angular stomatitis, dermatitis, corneal vascularisation, anemia, and brain dysfunction.
    Riboflavin is a potent antioxidant and offers particular benefits in protecting fatty tissues in the body suchasthebrain. TheseantioxidanteffectshavebeenshowntobebeneficialincasesofSICKLE CELL ANEMIA. Research has shown that riboflavin supplementation has led to significant improvements in iron status, (with increased total iron-binding capacity and serum ferritin) and glutathione levels.

    Riboflavin appears to be beneficial in treating lactic acidosis, common in AIDS patients, and in mitochondrial respiratory chain disorders such as infantile lactic acidosis, and skeletal myopathy / cardiomyopathy.

    Known contraindications - None known. Although correction of deficiency is warranted, individuals with cataracts should not use more than 10mg riboflavin per day due to photosensitivity effects.

    Interactions - The conversion of vitamin B6 to its active co-enzyme form P-5-P may be impaired in riboflavin deficiency. The conversion of riboflavin into its active coenzyme form is inhibited by thyroid and adrenal insufficiency; psychotropic drugs such as amitriptyline, chemotherapeutic drugs, and anti- malarial drugs.

    Alcohol causes riboflavin deficiency by interfering with both its digestion and intestinal absorption. Useful links - Migraine – Flax seed oil, quercetin complex, pycnogenol/grape seed extract.

    Note Riboflavin supplementation can result in a harmless yellow discolouration of the urine – it is thought that this effect is due to bacterial action on riboflavin, with metabolites then being absorbed and then excreted in the urine.

Vegan, Kosher, Veg Caps


Each of the Viridian B-complex supplements offers a full array of the B vitamins together with a higher level of a featured B vitamin. This supplement features a higher level of riboflavin (vitamin B2). B2 (riboflavin) contributes to the reduction of tiredness and fatigue, to normal psychological function, energy-yielding metabolism, the functioning of the nervous system and the maintenance of normal skin, vision, red blood cells, and mucous membranes. B2 also contributes to the protection of cells from oxidative stress. This 'oxidative stress' appears to be a major factor in many human diseases.

 

As a food supplement, take one capsule with food, or as directed by your healthcare professional.

One capsule provides:

Ingredient Weight %EC NRV
Vitamin B1 (Thiamin HCl) 200mg 14285
Vitamin B5 (as Calcium pantothenate) 50mg 833
Vitamin B3 (as Nicotinamide)  50mg 278
Vitamin B6 (as Pyridoxine HCl) 20mg 1000
Vitamin B2 (Riboflavin) 20mg 1250
Choline (Bitartrate) 8.2mg
Inositol 20mg
Biotin 0.2mg 135
Folic acid 200ug 100

Vitamin B12 (Adenosylcobalamin and Methylcobalamin)

20ug 2000
in a base of alfalfa, spirulina and bilberry