What do the different SARMS Selective Androgen Receptor Modulators do?

Posted by Mark Hamilton on

Lets have a quick look at the different SARMS avaiable at the moment.

I have been in the health and fitness industry since leaving school, so around 30 plus years now. I have seen products and companies come and go.

I have seen the popularity of differing physiques change, from super shredded to mass and bulk, back to shredded then bulk and shredded.

The technology we have access to now is amazing and the research being done is very exciting.

So we now come to a genuine game changer – SARM's Selective Androgen Receptor Modulators. I believe Genuine SARMs Like ours, are as good as steroids in most cases and that is a big statement to make.

Here is a general breakdown on the different sarms we have available and what they predominantly will do.


Cardarine is not actually a SARM – it is a PPAR-delta activator. This means it doesn’t directly influence the androgen receptors. Cardarine was initially researched for its fat-burning potential and further developed to potentially treat health issues around the heart and blood vessels. It is known to have a range of benefits for athletic performance and bodybuilding, including reduction of inflammation and increased fat-burning potential.

Helps maintain good blood flow to the brain

PPAR-delta activation increases fat burn and energy use

May even reverse symptoms of metabolic syndrome including liver fat and triglycerides

Lowers cholesterol

Increases nitric oxide to minimise oxidative damage to blood vessel

Lowers risk of heart disease

Suppresses inflammation (another benefit of activating the PPAR-delta pathway)

Encourages the liver to use fatty acids (to glucose) as energy which can reduce blood sugar

Better development of muscle fibres for strength, endurance, mass


Ostarine has been researched for its potential to reverse the effects of catabolism in muscle-wasting diseases and the ageing population. It is still in the clinical trial stage, making it one of the SARMs more likely to be approved for clinical use.

Ostarine is favoured by bodybuilders for its effects on muscle gain and strength gain with minimal risk of side effects.

SARMs results to expect from MK-2866:

Increases muscle mass and strength

Gives a dry, lean muscle gain appearance

Supports better fat loss without muscle loss

No water retention

Better pumps during training

Can reverse muscle loss (potentially when dieting in a calorie deficit)

No known impact on hormone levels

Beneficial for bone strength and bone density

Can lower cholesterol and blood glucose

May activate muscle satellite cells to help regenerate muscle tissue and connective tissue

No need for PCT or liver support supplements


Ibutamoren isn’t a SARM but a growth hormone secretagogue that is known to stimulate your natural production of growth hormone to increase GH levels. By increasing the body’s secretion of GH, it also increases IGF-1 (insulin-like growth factor) both of which are key anabolic hormones.

Ibutamoren binds to a part of the brain that plays a part in appetite.

Increases growth hormone secretion

Increases IGF-1

Improves muscle mass gain

Can reduce muscle loss during dieting phases

Boosts ability to lose body fat

Bone strength and bone density


LGD-4033 is often called the most potent of the SARM compounds. It was developed to improve patients’ recovery from fractures, because of its effect on tissue regeneration and strength.

Muscle mass gains (good choice for a bulk)

Fat loss (although may temporarily be masked by some water retention)

Strength increases

Bone density and bone strength

Positive effects on catabolism including cachexia

Can help retain muscle whilst dieting

Increased sense of wellbeing and libido


SR9009 is not a SARM, it is a REV-ERB agonist. It mediates optimal metabolic function being described often as an exercise mimetic, or something which can provide similar effects as can be expected from exercise.

Stenabolic was developed for its effects on the circadian rhythm – it enhances REV-ERB (the proteins which stabilise our internal body clock).

It has been shown to impact a number of health factors including anxiety, endurance, cholesterol, and inflammation.

SR9009 has the ability to affect weight loss without dieting, according to a 7-day study on mice.

Can impact the genes under circadian control

Potential to boost fat burn and increase mitochondria activity

“Turns off” the genes which encourage fat storage

Potent metabolism booster and fat burner

Enhances endurance and stamina

Enhance REV-ERB activity

Reduces fat and cholesterol

Reduces inflammation

Improves heart function

Promotes wakefulness

Combats anxiety

Non-stimulant and non-hormonal

Reduces levels of triglycerides and total cholesterol in the blood

Muscular endurance for improved training performance

Supports better mood and energy, reduces anxiety


SARMTestolone mimics testosterone but avoids the side effects of traditional testosterone supplements. It is being used in research for increasing muscle mass and protecting brain cells from degeneration.

SARMs results to expect from RAD-140:

More anabolic than testosterone

Anabolic to androgenic ratio of 90:1

A great addition to a prohormone cycle

Best for bulking cycles

Improves libido and sexual performance

Best SARM for muscle growth and size

Reduces fat and increases muscle mass

Ideal to enhance body composition

Rapid muscle recovery

A safer alternative to anabolic steroids

No androgenic side effects such as male pattern baldness

Excellent stacking potential with other SARMs 



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